An illustrative example of nucleophilic substitution involving different amines is the reaction between ethanolic ammonia and 1-bromopropane.

Nucleophilic substitution is a fundamental type of organic reaction where a nucleophile displaces a leaving group within a molecule. In the context of amines, the nucleophile is typically an amine molecule that replaces a halogen atom in an alkyl halide. For instance, when ethanolic ammonia interacts with 1-bromopropane, the bromine atom is substituted by an amino group, leading to the formation of propylamine.

The reaction between ethanolic ammonia and 1-bromopropane exemplifies a primary nucleophilic substitution reaction. In this process, the nucleophile attacks the carbon atom that is directly bonded to the leaving group. The reaction occurs through a transition state characterized by the partial breaking of the carbon-bromine bond and the partial formation of the carbon-nitrogen bond.

The rate of nucleophilic substitution reactions is influenced by various factors, including the nature of the nucleophile, the leaving group, and the solvent used. For example, primary amines tend to be more reactive than secondary or tertiary amines due to their higher electron density, which makes them stronger nucleophiles.

In summary, the nucleophilic substitution of various amines represents a common type of organic reaction that involves the replacement of a halogen atom in an alkyl halide with an amino group. The reaction rate and mechanism are contingent upon several factors, including the characteristics of the nucleophile, the leaving group, and the solvent employed.