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How do genetic mutations lead to variation?

Genetic mutations play a crucial role in generating variation by inducing changes in the DNA sequence of an organism’s genome.

A genetic mutation refers to an alteration in the DNA sequence that constitutes a gene. These changes can arise in various ways, such as through errors during DNA replication or as a result of exposure to environmental factors like radiation or specific chemicals. When a mutation occurs, it can modify the information encoded by the gene, potentially leading to the expression of different traits.

There are several types of mutations that can occur. One type involves changes to a single DNA base pair, known as point mutations. These mutations can result in the production of different amino acids, subsequently altering the structure and function of the proteins they comprise. Other mutations may affect larger segments of DNA, such as deletions or duplications of entire genes or even larger regions of a chromosome. Such mutations can significantly impact an organism’s traits, as they may lead to the loss or gain of entire genes.

Mutations contribute to variation within a population by creating new alleles, or alternative versions of genes. If a mutation occurs in a germ cell (the cells that develop into eggs or sperm), it can be transmitted to the next generation. Over time, these new alleles can spread through a population, fostering genetic diversity. This variation is a fundamental driver of evolution, as it provides the essential raw material for natural selection to act upon. Specifically, if a mutation confers a trait that enhances an organism’s survival in its environment, that organism is more likely to survive and reproduce, thereby passing the advantageous mutation to its offspring.

In summary, genetic mutations are a fundamental source of genetic variation. They introduce new genetic material into a population, leading to the expression of new traits. This variation is essential for the survival and evolution of species.

Answered by: Dr. Hannah Davies
GCSE Biology Tutor
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