Nitriles and amides are two distinct types of organic compounds characterized by different functional groups.

Nitriles are organic compounds that feature a triple bond between a carbon atom and a nitrogen atom. They are often referred to as cyanides and can be represented by the general formula $R-C \equiv N$, where $R$ signifies an alkyl or aryl group. Nitriles play a significant role in the manufacturing of synthetic rubber, plastics, and solvents. Additionally, they are present in various natural products, including alkaloids and amino acids. However, it is important to note that nitriles are highly toxic and can lead to cyanide poisoning if ingested or inhaled.

In contrast, amides are characterized by the presence of a carbonyl group ($C=O$) that is bonded to a nitrogen atom. They can be represented by the general formula $R-CO-NH_2$, where $R$ again denotes an alkyl or aryl group. Amides are integral components of proteins, nucleic acids, and other biomolecules. They are also utilized in the production of pharmaceuticals, polymers, and various industrial chemicals. Compared to nitriles, amides exhibit lower toxicity and are generally regarded as safe for human consumption.

In summary, nitriles and amides are two types of organic compounds distinguished by their functional groups. Nitriles contain a triple bond between a carbon and a nitrogen atom, while amides possess a carbonyl group bonded to a nitrogen atom. While nitriles are highly toxic, amides are typically considered safe for human use.